Sherlock Holmes

Jonny Lee Miller

Joan Watson

Lucy Liu

Captain Thomas Gregson

Aidan Quinn

Detective Marcus Bell

Jon Michael Hill

Odin Reichenbach

James Frain

Zachary Fowler

Danny Binstock

Detective Owen Calabrissi

Joseph Lyle Taylor

George Eagen

John Sharian

Captain Dwyer

Rob Bartlett

Dr. Eugene Hawes / Dr. Eugene Hawes

Jordan Gelber

Morland Holmes

John Noble

Kitty Winter

Ophelia Lovibond

Lanette Brooklee

Mandy Gonzalez

Paige

Virginia Madsen

DCI Athelney Jones

Tamsin Greig

Detective Farrad

Marjan Neshat

Annie Spellman

Kristen Bush

Ellory

Wrenn Schmidt

Tara Parker

Sutton Foster

Erika Vanderwey

Patricia Kalember

Agent Dean McNally

Tim Guinee

Naomi Long

Liz Carey

Sebastian Florenti

Gabriel Ebert

Antoine LaGrange

Daniel Davis

Colby

Nick Rehberger

Dr. Angela Hardy

Lindsay Mendez

Dr. Garret Halsey

Ravi Kapoor

Davis Whitmark

Myk Watford

Patrick Meers

Mac Brandt

Meredith Sagehorn

Christa Scott-Reed

Stewart Pringle/Wilson Kubiak

Charlie Semine

Antonia

Rachael Holmes

Olga Berezhnaya

Lili Mirojnick

Danielle Olivera

Kate Shindle

Ronald Adair

Simon Templeman

Tremaine

Terry Bell

Mrs. Tseng

Jodi Long

Mr. Hutchins

Michael Bryan French

Judd Foley

Charles Borland

Jason Wood

Chris Diamantopoulos

Hernan Zielenko

Robert Neary

Bree Novacek

Emily Swallow

Carla Whitmark

Stephanie DiMaggio

Ruby Carville

Saffron Burrows

Frederick Wentz

Bob Gunton

Lola Quinn

Maritz Veer

Mack Leehoven

Matthew Boston

Alejandro

Armando Acevedo

A.D.A. Garrison

Michael Hayden

Alfredo Llamosa

Ato Essandoh

Edward Cutler

David Beach

Derek Casey

Jamie Thomas King

Marty Bledsoe

Mike Houston

Dr. Gregory Burgess

Peter Ganim

Audrey Kensit

Shirley Rumierk

Sean

Ian Palmer

Wesley Conrad

Roderick Hill

Beth

Samantha Massell

Amos Deukmejian/DJ Pandasalt

Josiah Bania

Mycroft Holmes

Rhys Ifans

Aura Swenson

Kate Middleton

Jim Bendix

William Hill

Tony

Dave Shalansky

Enrique Ruiz

Carlos Gómez

Stan Veek

Zachary Knower

Chloe

January LaVoy

Janice

Kristolyn Lloyd

Rose

Shamika Cotton

Lisa Cooper

Kimberly S. Fairbanks

Tessa Pritchard

Kelly McCrann

Claire

Emma Kikue

Chip

Danny Schwarz

News Host

Joan Lunden

Detective Ocasio

Tramell Tillman

Security Coordinator

Andre Blake

Alwyn Smith

Ian Kahn

Beppo

Federico Dordei

Linda Blumenthal

April Ortiz

Caroline Gibbs

Carol Halstead

Mason

Robert Capron

Aura's Lawyer

Kate Levy

Eldon

Eric Elizaga

Ridley Dineen

Jason Babinsky

Jessi McNally

Nora Murphy

Peyton Trask

Brent Langdon

Guest 1

Stephen Dexter

Dalton Weller

Michael Satow

Arthur

Jonathan Han

Michael Bowen / Michael

Desmond Harrington

Nurse

Tara Summers

Lawyer

Mary McCann

Mr. Balfour

Alex Cranmer

Gene

Kristoffer Cusick

Lawyer

Judy McLane

Jake Goodel

Bubba Weiler

Amir

Sathya Sridharan

Ethiopian Consul

Lisa Arrindell

Guide

An-Li Bogan

Italian Woman

Caprice Benedetti

Lawyer

James Murtaugh

ToddHarris

Jeff Applegate

Officer Saldenbrook

Kario Marcel

Moped Man

Tom Vickers

Dylan Halleran

Sea McHale

Customer Service Rep

Tiffany Villarin

Cassie Lenue

Allie Ioannides

Esther Kelton

Pamela Dunlap

Suited Detective

Luis Moreno

Corinna Wood

Maddie Jo Landers

Reporter 1

Harry Smith

Viola Wright

Harriett D. Foy

Jersey Shore

Cody Calafiore

Propane Salesman

Gabe Doran

Lead ESU Officer

Yaegel T. Welch

Moped Man

Tom Vickers

ESU Sergeant

Diego Aguirre

Chip

Danny Schwarz

Assistant

Phumzile Sitole

Social Worker

Kelsey Rainwater

Mrs. Conrad

Lizbeth MacKay

Ms. Duarte

Maria Elena Ramirez

Irene Adler / Jamie Moriarty / Jamie Moriarty (voice)

Natalie Dormer

Plainclothes Cop

Mike Keller

Girlfriend

Autumn Guzzardi

Nicholas Gerrardi

Nathaniel Stampley

Benjamin Long

Joe Tippett

FBI Security Officer

Terrell Wheeler

Durah

Woodlene Alexis

Reporter 2

Ian Harkins

Reporter #1

Harry Smith

Cassina

Jennifer Mudge

Hannah Gregson

Liza J. Bennett

Team Leader

Jonathan Sale

Reporter #2

Ian Harkins

Lola Quinn

Maritza Veer

Arnold

Christopher Reed Brown

Juliana

Kirsten Scott

Carson Mayfield

Michael Siberry

Nurse

Erica Bradshaw

Chantal Milner

Chasten Harmon

Libby

Brynne McManimie

Elise

Winsome Brown

Sasha

Alyson Lange

Driver

Paco Lozano

Alicia Ocacia

Jade Radford

Andrew Paek

Raza Jaffrey

Guard 1

Marc Webster

TV Reporter / Reporter / TV News Anchor

Kristine Johnson

Director

Lucy Liu

Director

Guy Ferland

Director

Aaron Lipstadt

Director

Craig Zisk

Director

Seith Mann

Director

Thomas Carter

Director

Jerry Levine

Director

John Polson