Sherlock Holmes

Jonny Lee Miller

Joan Watson

Lucy Liu

Captain Thomas Gregson

Aidan Quinn

Detective Marcus Bell

Jon Michael Hill

Mycroft Holmes

Rhys Ifans

Alistair Moore

Roger Rees

Gareth Lestrade

Sean Pertwee

Cassandra Walker

Elizabeth Marvel

Lucas Bundsch

Troy Garity

Dr. Eugene Hawes

Jordan Gelber

Alfredo Llamosa

Ato Essandoh

Jamie Moriarty / Irene Adler / Jamie Moriarty (voice)

Natalie Dormer

Anne Barker/Abigail Spencer

Laura Benanti

Cheryl Gregson

Talia Balsam

Randy

Stephen Tyrone Williams

Joey Castoro

Jeremy Jordan

Emily Hankins

Susan Pourfar

Frank Da Silva

Peter Gerety

Iris Lanzer

Aleksa Palladino

Dr. Jonathan Fleming

Bruce Altman

Ezra Kleinfelter

Christian Campbell

Detective Gerry Coventry

Chris Bauer

Detective Nash

Danny McCarthy

Beth Roney

Sarah Wynter

Chloe Butler

Heather Burns

Gordon Cushing

Jeremy Davidson

Marchef

Henri Lubatti

Devon Gaspar

Andrew Howard

Tanya Barrett

Lynn Collins

Jerome Thomas

Jonno Roberts

Judge Brewster O'Hare

Frankie Faison

Lara Banin

Mia Barron

Stan Kovacevic

Robert Stanton

Ian

Ron Raines

Nigella Mason

Olivia D'Abo

Manny Rose

Ron Canada

Natalie Gale

Margaret Colin

Tim Sherrington

Ralph Brown

Graham Delancey

Sam Levine

Nolan Sharp

Scott Cohen

Miss Truepenny

Sarah Goldberg

Ian Gale

William Sadler

Dr. Paul Sutherland

Jeremy Shamos

Elliot Honeycutt

Ronald Guttman

Robert Pardillo

Paul Sorvino

Marion West

Emily Bergl

Sir James Walter

Jim Norton

Peri Delancey

Noelle Beck

Jennifer Sayles

Danielle Nicolet

Guillaume de Soto

Vincenzo Amato

Bart MacIntosh

Garret Dillahunt

DCI Hopkins

Tim McMullan

Detective Craig Basken

Peter Hermann

Ramses Mattoo

Faran Tahir

Dr. Phineaus Hobbs

Jordan Lage

Benny Charles

Khalil Kain

Tim Spalding

Eric Sheffer Stevens

Gay

Ashlie Atkinson

Tara Parker

Sutton Foster

Rachel Brown

Jennifer Laura Thompson

Sarah Cushing

Cara Buono

Richard Balsille

Bill Irwin

El Mecanico

Andrew Samonsky

Dalit Zirin

Shiri Appleby

Ruth Colville

Judith Ivey

Jacob Weiss

Richard Masur

Diego Salcedo

James Martinez

Titus Delancey

Steve Greenstein

Julian Afkhami

Nasser Faris

Maris

Orlagh Cassidy

Detective Annie Wozniak

Wendy Hoopes

Hank Prince

Mather Zickel

Michelle Forrester

Maggie Lacey

Morland Holmes

John Noble

Travis Hardwick

Wass Stevens

Lawrence Pendry

Rufus Wright

Harlan Emple

Rich Sommer

Detective Leslie Loughlin

Sue-Anne Morrow

Silas Cole

Zachary Booth

Agent Dean McNally

Tim Guinee

Celia Carroll

Laura Osnes

Tess Dahl

Teal Wicks

Cynthia Tilden

Charlotte Maier

James Monroe

Ted King

Haley Tyler

Kersti Bryan

Shawn Menck

Sean Nelson

Kayden Fuller

Delphina Belle

Cliff Brown

Dan Cooney

Apollo Mercer

Brandon Espinoza

Donald Hauser

Thomas Ryan

Karen Buckner

Gretchen Egolf

Miriam Berg

Phyllis Somerville

Kurt Yoder

Michael Gaston

Commissioner August Patrick

Brian Reddy

Milton Van Kirk

Peter McRobbie

Priest

John Owens

Marko Zubkov

Misha Kuznetsov

Joe Bey

Michael Medeiros

Kitty Winter

Ophelia Lovibond

Dr. Neil Murray

Christopher Fitzgerald