Sherlock Holmes
Jonny Lee Miller
Joan Watson
Lucy Liu
Captain Thomas Gregson
Aidan Quinn
Detective Marcus Bell
Jon Michael Hill
Michael Bowen / Michael
Desmond Harrington
Shinwell Johnson
Nelsan Ellis
John Hoyt
Victor Williams
Dr. Eugene Hawes / Dr. Eugene Hawes
Jordan Gelber
Alfredo Llamosa
Ato Essandoh
Lin
Samantha Quan
Morland Holmes
John Noble
David Horowitz
Christian Borle
Harlan Emple
Rich Sommer
Dr. Selsky
Nicole Shalhoub
Mason
Robert Capron
Hannah Gregson
Liza J. Bennett
Officer Rossi
Almeria Campbell
Cal Medina
Joaquim de Almeida
Nina Hudgins/Skyler
Marissa Neitling
Kevin
Kevin Ray
Chantal Milner
Chasten Harmon
Kyle Spikowski
Cody Kostro
Valentina Duran
Rosanny Zayas
The Nose
John Horton
Dr. Leo Demopoulos
James Urbaniak
Dr. Bridget Tanaka
Suzy Nakamura
William Bazemore
David Pittu
Sherry Lennox
Lesli Margherita
Luz Horowitz
Melissa De Sousa
Hunter Becket
James Barbour
Special Agent Mallick
Parminder Nagra
Jasper Wells
Julian Sands
Sepi Chamanara
Azita Ghanizada
Tara Parker
Sutton Foster
Graham Jenkins
Jacob Fishel
Ryan Hayes
Brett Dalton
Don Kohler
Alimi Ballard
Alden Lubbock
Jayce Bartok
Dominic Voth
Brian Stokes Mitchell
Chris Holland
Mike Doyle
Athena
Alia Attallah
Lauren Wexler
Erica Hernandez
Dudley Becket
Chelcie Ross
Merrick Hausmann
Stephen Spinella
Gary
Paul Anthony Stewart
Aldo Ventura
Tom Hewitt
Judge Marilyn Whitfield
Tonya Pinkins
Father Cantu
Luis Antonio Ramos
Alfonse Templeton
Maulik Pancholy
Gay
Ashlie Atkinson
Go Shinura
Louis Ozawa Changchien
Sophie Bush
Trieste Kelly Dunn
Dr. Vit Parnthong
Katherine Sigismund
Krista
De'Adre Aziza
Detective Mason
James Monroe Iglehart
Lawyer
Kate Levy
Jonathan Dawson
Babak Tafti
Strider Lincoln
Clarke Thorell
Professor Baynes
Ian Hart
Officer Myers
Jimmy Brooks
Dave Amberlin
Thomas Keegan
Agent Polk
Brandon J. Dirden
Denny Mulgrew
Dan Butler
Adrian Cruz
Juan Carlos Hernández
Sydney Place
Douglas Hodge
Felipe
Gonzalo Menendez
Marvin Hathaway
Ned Eisenberg
Colm Frick
Jamie Jackson
Hakeem
Dion Graham
Evan Kowalski
Kevin Cahoon
Drew Bishop
Wayne Wilcox
Eddy Dunbridge
Frank Harts
Kitty Winter
Ophelia Lovibond
Levi Salinger
Jeb Brown
Detective Scandrick
Elena Hurst
Curtis Jenkins
Edward James Hyland
Doctor
Eden Espinosa
Doron
Chris Ashworth
Valerie Field
Jolly Abraham
Irvin Langstrom
Mark Blum
Paula Rodriguez
Rosal Colon
Kip Lowell
Roger Bart
Agent Kerner
Nana Mensah
Armored Truck Driver
Matthew Montelongo
Dr. Ziegler
Ben Van Bergen
Maya
Kristin Villanueva
Vernon Fisk
Geoffrey Owens
Mr. Clay
Reg E. Cathey
Natalie Park
Rona Figueroa
Angela Donnely
Jenna Stern
Jesus Rodriguez
Gerardo Rodriguez
Lance Pickering
Graham Winton
Tim Darsha/Agent Bakshi
Pej Vahdat
Midnight Ranger
Tyler Hanes
Burly Man
David Park
Rohan Giri
Alok Tewari
Bodyguard
Geno Segers
Terry Weaver
Olli Haaskivi
Blaine Geary
Jimmie Saito
Sylvia Kozar
Siobhan Fallon Hogan
Lt. Colonel Robin Deakins
LisaGay Hamilton
H.R. Rep
Sarah Clements
King Wilhelm
Paul Collins
Councilman Vucelich
Michael Cerveris
Sophia
Aditi Shah
Mycroft Holmes
Rhys Ifans
Richie
Alex Hurt
FBI Suit 1
Stephen Conrad Moore
Adam Braun
Steven Robertson
Sammy Olivetti
Trevor Van Uden
Maria
Naomi Lorrain
Bodyguard
Shawn Cortel
Ramon
Ricky Garcia
Treadwell
John Dossett
Seth Dwyer
Bob Walton
Milt Reed
John Hillner
Cashier/Ellory
Wrenn Schmidt
Chloe Giri
Alexandra Silber
Derek Clay
Sean Meehan
Marjorie
Portia
Anthony Daniels
Leon Addison Brown
Henry Baskerville
Tom Everett Scott
Dr. Elk
Sydney James Harcourt
Marcy Nix
Gia Crovatin
Major Joshua Beckham
Maurice Jones
Dr. Ken Fukata
James Saito
Armand Venetto
Dylan Baker
Foreman
Danny Garcia
Bethany Marshall
Summer Sveinson
Troy Roselli
Tony Manna
Ricky
Fedna Jacquet
Manager
Lawrence Clayton
Lacey
Catherine Oliviere
Walter Petty
Briane Keane
Debora Garissi
Margaret Odette
Hernan Cortes
Raul Aranas
Dr. Peter Hanson
Michael Potts
Detective 1
David Shih
Prashant Hobbs
C.J. Wilson
Moira Baker
Anne L. Nathan
Young Detective
Irene Sofia Lucio
ESU Officer
Alexis Suarez
Lloyd
Alton Fitzgerald White
Foreman
J. Oscar Simmons
Nick
Devin Harjes
General Howard Alvero
Tony Plana
Attendant 1
Josh Bonzie
Angelo
Kyle Vincent Terry
Uni 1
Chris Carlock
Louie
Brian Gonzales
Victoria Garvey
Lynne Winterstellar
Rupert Hong
Ben Graney
Tony
Neal Gupta
Older Detective
Gilbert Cruz
Paul Chambers
Arnie Burton
Bethany Ito
Deborah S. Craig
Cerio Cristobal
Francisco Burgos
Imposter
Johnny Hopkins
Boss
Terence Archie
Karen
Sarah Litzsinger
Lowell's VP
Phil McGlaston
Eli
Stephen Schnetzer
Art Schultz
Adam Dannheisser
Jaylen Thomas
Hubert Point-Du Jour
The Dutchman
Lukas Hassel
Foreman
J. Oscar Simmons
Bethany Marshall
Summer Sveinson
Gary
Asher Grodman
Lord St. Simon
Julian Nicholas Elfer
Bingo Host
Susan Varon
Elijah Robinson
Maurice McRae
Vikrant Jindal
Samrat Chakrabarti
Sean O'Grady
Michael Rispoli
Gwen Haeny
Paloma Guzman
Gus Chipman
Johnny Wu
Brian
Ron Menzel
Kezzy
Nadia Gan
ESU Commander
Shawn T. Andrew
Detective Mori
Jason Alan Carvell
Odin Reichenbach
James Frain
Fake Cop 1
Jed Peterson
Maddie
Comfort Clinton
Tara Keane
Emma Geer
Cora
Amelia Workman
Kelsey Chapman
Michele Selene Ang
Sir James Walter
Jim Noton
Lily Zavala
Isabel Arraiza
Uni 2
Byron Bronson
Hugo Irving
Matthew Maher
Beauregard "Bud" Granville
Brendan Patrick Connor
Elderly Woman
Jade Wu
Guard
Lawrence Ballard
Collins
Niels Jorgensen
Female Surgeon
Lisa Tharps
Mrs. Holland
Ami Sheth
Agent Dean McNally
Tim Guinee
Quinn
Nedra McClyde
Cop 1
Jorge Luna
Phillip Bridwell
Phillip James Brannon
Bob
Brian Sills
Kwan
Jeffrey Omura
George Nix
Robert Vincent Smith
Wade
Lance Coadie Williams
Fred
Adam Petchel
Maggie Foltz
Twinkle Burke
Romy
Jinette Dilone
Irene Adler / Jamie Moriarty / Jamie Moriarty (voice)
Natalie Dormer
Vanja Borozan
Pawel Szajda
Zeke
Timothy D. Stickney
Female Firefighter
Cherelle Cargill
Cop 2
Joseph Castillo-Midyett
David
Bruce Sabath
Allison
Christiani Pitts
Melville
Will Blum
Javi
Freddy Miyares
Anxious Woman
Beth Fowler
Nick Evaneer
Jason Manuel Olazabal
Security Guard
Rashad Edwards
Sophomore Boy
Matthew Schechter
Dan
Gordon Winerick
Jeff Stanton
Joe Carroll
Mallory
Merritt Janson
Dr. Amelia Furing
Karen Ziemba
Lydia Winchell
Meredith Garretson
Donnie Mainzer
Pete McElligott
Captain Dwyer
Rob Bartlett
Becca Mainzer
Carrie St. Louis
Andrew Paek
Raza Jaffrey
TV Reporter / Reporter / TV News Anchor
Kristine Johnson
Linda Emond
Susan Pourfar
Sophie Bishop
Kelly Dunn
Landlady
Sandy Dell
Detective
Annie Pisapia
CSU Tech
James Zeiss