Peter Parker/Spider-Man

Tobey Maguire

Green Goblin / Norman Osborn

Willem Dafoe

Mary Jane Watson

Kirsten Dunst

Harry Osborn

James Franco

Ben Parker

Cliff Robertson

Ben Parker

Cliff Robertson

May Parker

Rosemary Harris

J. Jonah Jameson

J.K. Simmons

Flash Thompson

Joe Manganiello

Maximillian Fargas

Gerry Becker

Joseph "Robbie" Robertson

Bill Nunn

Henry Balkan

Jack Betts

Henry Balkan

Jack Betts

General Slocum

Stanley Anderson

Dr. Mendel Stromm

Ron Perkins

Carjacker

Michael Papajohn

Simkins

K.K. Dodds

Hoffman

Ted Raimi

Simkins

K. K. Dodds

Ring Announcer

Bruce Campbell

Miss Brant

Elizabeth Banks

Houseman

John Paxton

Philip Watson

Tim DeZarn

Madeline Watson

Taylor Gilbert

Bone Saw McGraw

Randy Savage

Wrestling Promoter

Larry Joshua

Bone Saw McGraw

Randy Poffo

Wrestling Arena Guard

Timothy Patrick Quill

Bone-ette

Lisa Danielle

Bone-ette

Natalie T. Yeo

Bone-ette

Erica D. Porter

Bone-ette

Kristen Davidson

Flash's Crony

Jason Padgett

Teacher

Shan Omar Huey

Doctor

Evan Arnold

Girl on Bus

Sally Levi

Nurse

Jill Sayre

Project Coordinator

Jim Ward

Test Pilot

David Holcomb

Check-In Girl

Octavia Spencer

Heckler

Brad Grunberg

Billy's Mom

Deborah Wakeham

Times Square Child

Rachael Bruce

Times Square Child

Mackenzie Bryce

Little Billy

Shane Habberstad

Times Square Child

Julia Barrie

Macy Gray

Macy Gray*

Cop at Fire

Myk Watford

Fireman

Bill Calvert

Macy Gray

Macy Gray

Mother at Fire

Sylva Kelegian

Young Lady at Fire

Kristen Marie Holly

Cabbie

Ajay Mehta

Cabbie

Peter Appel

Marine Cop

Scott Spiegel

Cop at Carjacking

Matt Smith

Cop at Carjacking

Sara Ramirez

Punk Rock Girl

Lucy Lawless

Subway Guitarist

Jayce Bartok*

Lady Dogwalker

Maribel González

Office Lady

Amy Bouril

Opinionated Cop

Joseph D'Onofrio

Subway Guitarist

Jayce Bartok

Surly Truck Driver

Jim Norton

Chaperone in Tram

Corey Mendell Parker

Girl in Tram

Ashley Edner

Boy in Tram

William Joseph Firth

Surly Truck Driver

Jim Norton

Boy in Tram

Alex Black

Tram Group Mother

Laura Gray

New Yorker on Bridge

Joe Virzi

New Yorker on Bridge

Michael Edward Thomas

New Yorker on Bridge

Jeanie Fox

Tugboat Captain

Robert Kerman

Lab Tour Guide (uncredited)

Una Damon

Colonel (uncredited)

Peter Aylward

Crying Girl in Tram (uncredited)

Jillian Clare

Kyle (uncredited)

Chris Coppola

Spectator at School Fight (uncredited)

Jesse Heiman

World Unity Festival Attendant (uncredited)

Leroy Patterson

Mugger (uncredited)

Benny Urquidez

Screaming Wrestler (uncredited)

Scott L. Schwartz

Chef (uncredited)

Jophery C. Brown

Young Thug #2 (uncredited)

Brian J. Williams

Uptown Woman (uncredited)

Tia Dionne Hodge

Balkan's Aide (uncredited)

Andray Johnson

Thug on 8x10 (uncredited)

Martin Pfefferkorn

Mary Jane's Friend (uncredited)

Lindsay Thompson

Pentagon Officer (uncredited)

Pete MacNamara

Director

Sam Raimi