Peter Parker / Spider-Man

Andrew Garfield

Gwen Stacy

Emma Stone

Dr. Curt Connors / The Lizard

Rhys Ifans

Capt. Stacy

Denis Leary

Richard Parker

Campbell Scott

Uncle Ben

Martin Sheen

Rajit Ratha

Irrfan Khan

Aunt May

Sally Field

Mary Parker

Embeth Davidtz

Peter Parker (Age 4)

Max Charles

Flash Thompson

Chris Zylka

Jack's Father

C. Thomas Howell

Jack

Jake Keiffer

Jack

Jake Ryan Keiffer

Helen Stacy

Kari Coleman

Missy Kallenbeck

Hannah Marks

Store Clerk

Michael Barra

Cash Register Thief

Leif Gantvoort

Gordon

Andy Pessoa

Mr. Cramer

Kevin McCorkle

Physics Nerd

Andy Gladbach

Sally Avril

Kelsey Asbille

Physics Nerd

Ring Hendricks

Miss Ritter

Barbara Eve Harris

School Librarian

Stan Lee

Physics Nerd

Ring Hendricks-Tellefsen

Nicky's Girlfriend

Danielle Burgio

Nicky

Tom Waite

Car Thief

Keith Campbell

Car Thief Cop

Steve Decastro

Receptionist

Jill Flint

OsCorp Intern

Mark Daughtery

Rodrigo Guevara

Milton Gonzalez

Howard Stacy

Skyler Gisondo

OsCorp Intern

Mark Daugherty

Phillip Stacy

Charlie DePew

Simon Stacy

Jacob Rodier

Construction Worker

Vincent Laresca

Taxi Driver

Damien Lemon

Police Officer With Sketch

Ty Upshaw

Police Officer

James Chen

Officer (SWAT)

Alexander Bedria

Sheila (Subway)

Tia Texada

Subway Guy

Jay Caputo

Principal

Terry Bozeman

Second Girl (Subway)

Jennifer Lyons

Newscaster (News Chopper)

John Burke

Man in the Shadows

Michael Massee*

Ariel

Amber Stevens