Tommy Pickles

Elizabeth Daily

Drew Pickles

Michael Bell

Didi Pickles (voice)

Melanie Chartoff

Chuckie Finster

Christine Cavanaugh

Phil DeVille / Lil DeVille (voice)

Kath Soucie

Angelica Pickles (voice)

Cheryl Chase

Kimi Finster (voice)

Dionne Quan

Phil/Lil

Kath Soucie*

Dil Pickles / Timmy McNulty (voice)

Tara Strong

Stu Pickles (voice)

Jack Riley

Melinda Finster

Kim Cattrall

Grandpa Lou Pickles (voice)

Joe Alaskey

Grandpa Lou

Joe Alaskey*

Captain

Vic Polizos

Lucy Carmichael

Cheryl Carter

Plumber

Andrew "Dice" Clay

Weatherman

Nathan Carlson

Grandpa Lou Pickles

David Doyle

Shlomo

Fyvush Finkel

Reptar/Knight

Jesse Corti

Susie Carmichael (voice)

Cree Summer

Howard DeVille

Phil Proctor

Jack Montello/Diner 2

Joe Mantegna

Carwash Owner/Cashier

John Byner

Joey

Benjamin Caya

Mr. Turkey

Dee Bradley Baker

Charlotte Pickles (voice)

Tress MacNeille

Sal/Vinnie

John Rubano

Frankie

Gregory Grudt

Radio Announcer/Masked Detective

Erv Immeman

Herbert

Brennan Louie

Salesman/Announcer

Sam Anderson

Dr. Brander

Laura Innes

Rabbi/Old Man

Ron Leibman

Ricky

Courtland Mead

Security

Gregg Berger

Bully

Mona Marshall

Larry

Jeremy Sisto

Story Reader

Leigh Taylor-Young

Frank/Announcer

Roger Nolan

Vinnie

Robert Costanzo

Dr. Lipschitz

Tony Jay

Lowell/Greek Bully/Donut Man

Alan Rachins

Mr. Koch/Juggler

Robert Morse

Announcer

Andre Carthen

Terry McNulty/Todd McNulty

Grey DeLisle

Sasha

Charity Sanoy

Actor/Sentry

Alan Paul

Chuckie Finster (voice)

Nancy Cartwright

Mr. Dreidel/TV Announcer

Alan Rosenberg

Tony/Diner 1

Vinny Montello

Miss Appleby

Marcia Strassman

Rob Hackett

Mark DeCarlo

Taffy

Amanda Bynes

Trash Guy/Sergeant

Kevin Michael Richardson

Lou at Age 20/Delivery Man

Scott Weil

—

Neil Ross

—

Hadley Kay

—

Scott Menville

—

Tony Jay

—

Ron Glass

—

Jeremy Piven

Director

Pete Michels

Director

Craig Bartlett

Director

Raymie Muzquiz