Michael Burnham

Sonequa Martin-Green

Saru

Doug Jones

Captain Gabriel Lorca

Jason Isaacs

Emperor Philippa Georgiou / Captain Philippa Georgiou

Michelle Yeoh

Sylvia Tilly

Mary Wiseman

Lieutenant Ash Tyler

Shazad Latif

Paul Stamets

Anthony Rapp

Dr. Hugh Culber

Wilson Cruz

Keyla Detmer

Emily Coutts

Rhys

Patrick Kwok-Choon

T'Kuvma

Chris Obi

Joann Owosekun

Oyin Oladejo

L'Rell

Mary Chieffo

Lt. / Lt. Cmdr. R.A. Bryce / Comms Officer 2

Ronnie Rowe

Ambassador Sarek

James Frain

Harry Mudd

Rainn Wilson

Cleveland 'Book' Booker

David Ajala

Terry Serpico

Commander Landry

Rekha Sharma

Lt. Nilsson / Airiam

Sara Mitich

Adira Tal

Blu del Barrio

Kol

Kenneth Mitchell

Dr. Nambue

Maulik Pancholy

Dennas

Clare McConnell

Ujilli

Damon Runyan

Linus / Kelpien Villager #1 / Young Su'Kal

David Benjamin Tomlinson

Discovery Computer (voice) / EV Suit Computer (voice) / Sanctuary Voice (voice)

Julianne Grossman

Ensign Connor

Sam Vartholomeos

Zora (voice)

Annabelle Wallis

Cmdr. Jett Reno

Tig Notaro

Dr. Pollard

Raven Dauda

Gray Tal

Ian Alexander

President T'Rina

Tara Rosling

Lt. Christopher

Orville Cummings

Christopher Pike

Anson Mount

Cmdr. Nhan

Rachael Ancheril

Lt. Cmdr. Airiam

Hannah Cheesman

Admiral Katrina Cornwell

Jayne Brook

UFP President Laira Rillak

Chelah Horsdal

Rayner

Callum Keith Rennie

Dr. Kovich

David Cronenberg

Spock / Spock (voice)

Ethan Peck

Book's Ship Computer (voice)

Fabio Tassone

Malinne 'Moll' Ravel

Eve Harlow

Amanda Grayson

Mia Kirshner

Leland

Alan Van Sprang

Klingon / Yeoman Colt / Orion Delegate

Nicole Dickinson

Lt. Ina / Kelpien Council Member #2 / Captain Rahma

Avaah Blackwell

Ruon Tarka

Shawn Doyle

Lt. Gallo

Natalie Liconti

Lt. Naya

Victoria Marie

Lt. Cmdr. Asha

Christina Dixon

Young Michael Burnham

Arista Arhin

L'ak / Cold

Elias Toufexis

Ndoye

Phumzile Sitole

Shenzhou Computer (voice)

Tasia Valenza

Andorian Regulator / Admiral Shukar / Andorian Admiral

Riley Gilchrist

Lt. Audrey Willa

Vanessa Jackson

Dr. Gabrielle Burnham

Sonja Sohn