Michael Burnham
Sonequa Martin-Green
Saru
Doug Jones
Emperor Philippa Georgiou / Captain Philippa Georgiou
Michelle Yeoh
Lt. Cmdr. Paul Stamets
Anthony Rapp
Sylvia Tilly
Mary Wiseman
Ash Tyler
Shazad Latif
Captain Christopher Pike
Anson Mount
Dr. Hugh Culber
Wilson Cruz
Sarek
James Frain
Lt. / Lt. Cmdr. Keyla Detmer
Emily Coutts
Lt. / Lt. Cmdr. Joann Owosekun
Oyin Oladejo
Amanda Grayson
Mia Kirshner
L'Rell
Mary Chieffo
Spock
Ethan Peck
Commander (Cmdr.) Jett Reno
Tig Notaro
Lt. / Lt. Cmdr. Gen Rhys
Patrick Kwok-Choon
Comm Officer 2 / Lt. / Lt. Cmdr. R.A. Bryce
Ronnie Rowe
Lt. Cmdr. Airiam
Hannah Cheesman
Number One
Rebecca Romijn
Cleveland 'Book' Booker
David Ajala
Lt. / Lt. Cmdr. Nilsson / Airiam
Sara Mitich
Adira Tal
Blu del Barrio
Lt. Connolly
Sean Connolly Affleck
Discovery Computer (voice) / Sanctuary Voice (voice)
Julianne Grossman
Cmdr. Nhan
Rachael Ancheril
Lt. J.G. Linus the Saurian / Young Su'Kal / Cosmo Traitt
David Benjamin Tomlinson
Young Michael Burnham
Arista Arhin
Fleet Admiral Charles Vance
Oded Fehr
Dr. / Cmdr. Tracy Pollard
Raven Dauda
Gabriel Lorca
Jason Isaacs
Young Spock
Liam Hughes
Dr. Nambue
Maulik Pancholy
Lt. Ina / Kelpien Council Member #2 / Captain Rahma
Avaah Blackwell
Admiral Katrina Cornwell
Jayne Brook
Zora (voice)
Annabelle Wallis
President T'Rina
Tara Rosling
Raynor
Callum Keith Rennie
Gray Tal
Ian Alexander
Federation President Laira Rillak
Chelah Horsdal
Kol / Invigilator Aurellio / Kol-Sha
Kenneth Mitchell
Book's Ship Computer (voice)
Fabio Tassone
Leland
Alan Van Sprang
Yeoman Colt / Klingon / Orion Delegate
Nicole Dickinson
Ruon Tarka
Shawn Doyle
Kovich
David Cronenberg
Lt. Christopher
Orville Cummings
Young Michael Burnham
Arista Arhin
Ndoye
Phumzile Sitole
Shenzhou Computer (voice)
Tasia Valenza
Commander Landry
Rekha Sharma
Andorian Regulator / Admiral Shukar / Andorian Admiral
Riley Gilchrist
Lt. Audrey Willa
Vanessa Jackson
Dr. Gabrielle Burnham
Sonja Sohn