Michael Burnham

Sonequa Martin-Green

Saru

Doug Jones

Captain Lorca

Jason Isaacs

Paul Stamets

Anthony Rapp

Emperor Philippa Georgiou / Captain Philippa Georgiou

Michelle Yeoh

Sylvia Tilly

Mary Wiseman

Lt. Tyler

Shazad Latif

Dr. Hugh Culber

Wilson Cruz

Cleveland 'Book' Booker

David Ajala

Lt. / Lt. Cmdr. Keyla Detmer

Emily Coutts

Lt. / Lt. Cmdr. Joann Owosekun

Oyin Oladejo

Adira

Blu del Barrio

T'Kuvma

Chris Obi

L'Rell

Mary Chieffo

Lt. / Lt. Cmdr. Gen Rhys

Patrick Kwok-Choon

Gray Tal

Ian Alexander

Comm Officer 2 / Lt. / Lt. Cmdr. R.A. Bryce

Ronnie Rowe

Commander (Cmdr.) Jett Reno

Tig Notaro

Sarek

James Frain

Harry Mudd

Rainn Wilson*

Brett Anderson

Terry Serpico

Lt. / Lt. Cmdr. Nilsson / Airiam

Sara Mitich

Dr. Nambue

Maulik Pancholy

Ujilli

Damon Runyan

Commander Landry

Rekha Sharma

Kol / Invigilator Aurellio / Kol-Sha

Kenneth Mitchell

Discovery Computer (voice) / Sanctuary Voice (voice)

Julianne Grossman

Dennas

Clare McConnell

Lt. J.G. Linus the Saurian / Young Su'Kal / Cosmo Traitt

David Benjamin Tomlinson

Ensign Connor

Sam Vartholomeos

Fleet Admiral Charles Vance

Oded Fehr

Capt. Christopher Pike

Anson Mount

Spock / Spock (voice)

Ethan Peck

Admiral Katrina Cornwell

Jayne Brook

Cmdr. Nhan

Rachael Ancheril

Lt. Cmdr. Airiam

Hannah Cheesman

Zora (voice)

Annabelle Wallis

President T'Rina

Tara Rosling

Raynor

Callum Keith Rennie

Federation President Laira Rillak

Chelah Horsdal

Book's Ship Computer (voice)

Fabio Tassone

Amanda Grayson

Mia Kirshner

Leland

Alan Van Sprang

Yeoman Colt / Klingon / Orion Delegate

Nicole Dickinson

Ruon Tarka

Shawn Doyle

Lt. Ina / Kelpien Council Member #2 / Captain Rahma

Avaah Blackwell

Kovich

David Cronenberg

Lt. Christopher

Orville Cummings

Young Michael Burnham

Arista Arhin

Ndoye

Phumzile Sitole

Shenzhou Computer (voice)

Tasia Valenza

Number One

Rebecca Romijn

Andorian Regulator / Admiral Shukar / Andorian Admiral

Riley Gilchrist

Lt. Audrey Willa

Vanessa Jackson

Dr. Gabrielle Burnham

Sonja Sohn

Dr. / Cmdr. Tracy Pollard

Raven Dauda