Vanya Hargreeves / Number Seven / Viktor Hargreeves

Elliot Page

Number Five

Aidan Gallagher

Luther Hargreeves

Tom Hopper

Hazel

Cameron Britton

Young Allison

Eden Cupid

Diego Hargreeves

David Castañeda

Allison Hargreeves

Emmy Raver-Lampman

Young Luther

Cameron Brodeur

Young Ben

Ethan Hwang*

Klaus Hargreeves

Robert Sheehan

Ben Hargreeves / Number Six

Justin H. Min

Sir Reginald Hargreeves

Colm Feore

Lila Pitts

Ritu Arya

Pogo (voice)

Adam Godley

Marcus

Justin Cornwell

Fei

Britne Oldford

Young Vanya

T.J. McGibbon

Grace

Jordan Claire Robbins

Alphonso

Jake Epstein

Sloane

Genesis Rodriguez

The Handler

Kate Walsh

Raymond Chestnut

Yusuf Gatewood

Jayme

Cazzie David

Cha-Cha

Mary J. Blige

Stan

Javon "Wanna" Walton

Syd

Murray Furrow

Agnes

Sheila McCarthy

Detective Eudora Patch

Ashley Madekwe

Sissy Cooper

Marin Ireland

Leonard Peabody

John Magaro

Herb / Pogo Body

Ken Hall

Axel

Kristen Holden-Ried

Otto

Jason Bryden

Young Klaus

Dante Albidone

Carl Cooper

Stephen Bogaert

Chet Rodo

Julian Richings

Young Diego

Blake Talabis

Dot

Patrice Goodman

Elliot

Kevin Rankin

Stan

Javon Walton

Detective Chuck Beaman

Rainbow Sun Francks

Older Five / Super Old Five / Middle Aged 5

Sean Sullivan

Oscar

Tom Sinclair

Keechie

Dov Tiefenbach

Lester Pocket

Callum Keith Rennie

Abigail Hargreeves

Liisa Repo-Martell

Dr. Gene Thibedeau

Nick Offerman

Dr. Jean Thibedeau

Megan Mullally

Claire Hargreeves

Millie Davis

Young Vanya (Age 4)

Alyssa Gervasi

Jack Ruby

John Kapelos

Young Dave

Calem MacDonald

Gruff Manager

Tony Marra

Wife / Lila's Mom

Shiva Safari

Jennifer

Victoria Marie

Director

Andrew Bernstein

Director

Sylvain White

Director

Peter Hoar

Director

Stephen Surjik

Director

Jeremy Webb

Director

Ellen Kuras

Director

Paco Cabezas