Penny

Kaley Cuoco

Leonard Hofstadter

Johnny Galecki

Sheldon Cooper

Jim Parsons

Howard Wolowitz

Simon Helberg

Raj Koothrappali

Kunal Nayyar

Amy Farrah Fowler

Mayim Bialik

Bernadette Rostenkowski

Melissa Rauch

Priya Koothrappali

Aarti Mann

Debbie Wolowitz (voice)

Carol Ann Susi

President Siebert

Joshua Malina

Dr. V.M. Koothrappali

Brian George

Barry Kripke

John Ross Bowie

Jimmy Speckerman

Lance Barber

Stuart Bloom

Kevin Sussman

Reverend White

Jim Turner

Mary Cooper

Laurie Metcalf

Kevin

Blake Berris

Dr. Beverly Hofstadter

Christine Baranski

Sandy

Stacey Travis

Mike Rostenkowski

Casey Sander

Althea

Vernee Watson

Jimmy

Karl T. Wright

Mrs. Koothrappali

Alice Amter

Jonathan

Jonathan Schmock

Stephen Hawking

Stephen Hawking

Siri

Becky O'Donohue

Laura

Ashley Austin Morris

Dale

Josh Brener

Phil

Nick Clifford

Alice

Courtney Ford

Dave Roeger

Robert Clotworthy

Emily

Katie Leclerc

Lakshmi Choudry

Chriselle Almeida

Aaron

Jadon Sand

Professor Rothman

Lynn Philip Seibel

Wil Wheaton

Wil Wheaton

Mike Massimino

Mike Massimino

Angelo

Peter Onorati

Mr. Spock

Leonard Nimoy

Brent Spiner

Brent Spiner

Dimitri

Pasha Lychnikoff

Jeremy

Dusan Brown

Emily Sweeney

Laura Spencer

Bert Kibbler

Brian Posehn

Zack Johnson

Brian Thomas Smith

Halley Wolowitz (voice)

Pamela Adlon

Leslie Winkle

Sara Gilbert

Anu

Rati Gupta

Lucy

Kate Micucci

Steven V. Silver

Denise

Lauren Lapkus

Mark Cendrowski

Richard Williams

Dean Norris

Chuck Lorre

Maria Ferrari

Michael J. Massimino

Michael J. Massimino

Bill Prady

Janine Davis

Regina King

Arthur Jeffries

Bob Newhart

Steven Molaro

Claire

Alessandra Torresani

Faye Oshima Belyeu

Eric Gablehauser

Mark Harelik

Announcer (voice) / Lecturer (voice) / Man V.O. (voice)

Ed Lieberman

Wyatt Teller

Keith Carradine

Iris Bahr