Leonard Hofstadter
Johnny Galecki
Sheldon Cooper
Jim Parsons
Penny
Kaley Cuoco
Howard Wolowitz
Simon Helberg
Raj Koothrappali
Kunal Nayyar
Amy Farrah Fowler
Mayim Bialik
Bernadette Rostenkowski
Melissa Rauch
Dr. V.M. Koothrappali
Brian George
Stuart Bloom
Kevin Sussman
Stephen Hawking
Stephen Hawking
Zack Johnson
Brian Thomas Smith
Emily Sweeney
Laura Spencer
Issabella
Maria Canals-Barrera
Theodore
Christopher Lloyd
Doug
Joel Murray
Althea
Vernee Watson
Marty
Josh Zuckerman
Barry Kripke
John Ross Bowie
Computer Voice
Kimberly D. Brooks
Dr. Ramona Nowitzki
Riki Lindhome
Lucy
Kate Micucci
Dr. Beverly Hofstadter
Christine Baranski
Debbie Wolowitz (voice)
Carol Ann Susi
Bert Kibbler
Brian Posehn
Mrs. Petrescu
Michelle Arthur
Claire
Alessandra Torresani
Rebecca
April Bowlby
Mary Cooper
Laurie Metcalf
Halley Wolowitz (voice)
Pamela Adlon
Guest Star
Kunal Dudheker
Emily
Katie Leclerc
The Flash
Brandon Jones
Wil Wheaton
Wil Wheaton
Dr. Alfred Hofstadter
Judd Hirsch
Nolan
Josh Banday
Wyatt Teller
Keith Carradine
Daniel
Bryan Safi
Susan
Katey Sagal
Christopher
Tucker Albrizzi
President Siebert
Joshua Malina
Randall
Jack McBrayer
Jeff
Jareb Dauplaise
Colonel Richard Williams
Dean Norris
Anu
Rati Gupta
Denise
Lauren Lapkus
Mike Rostenkowski
Casey Sander
Michael J. Massimino
Michael J. Massimino
Janine Davis
Regina King
Arthur Jeffries
Bob Newhart
Eric Gablehauser
Mark Harelik
Announcer (voice) / Man / Man V.O. (voice)
Ed Lieberman
Sheldon Cooper
Jim Parsons
Dimitri
Pasha D. Lychnikoff
Aarti Mann