Leonard Hofstadter

Johnny Galecki

Sheldon Cooper

Jim Parsons

Penny

Kaley Cuoco

Howard Wolowitz

Simon Helberg

Raj Koothrappali

Kunal Nayyar

Amy Farrah Fowler

Mayim Bialik

Bernadette Rostenkowski

Melissa Rauch

Dr. V.M. Koothrappali

Brian George

Stuart Bloom

Kevin Sussman

Stephen Hawking

Stephen Hawking

Zack Johnson

Brian Thomas Smith

Emily Sweeney

Laura Spencer

Issabella

Maria Canals-Barrera

Theodore

Christopher Lloyd

Doug

Joel Murray

Althea

Vernee Watson

Marty

Josh Zuckerman

Barry Kripke

John Ross Bowie

Computer Voice

Kimberly D. Brooks

Dr. Ramona Nowitzki

Riki Lindhome

Lucy

Kate Micucci

Dr. Beverly Hofstadter

Christine Baranski

Debbie Wolowitz (voice)

Carol Ann Susi

Bert Kibbler

Brian Posehn

Mrs. Petrescu

Michelle Arthur

Claire

Alessandra Torresani

Rebecca

April Bowlby

Mary Cooper

Laurie Metcalf

Halley Wolowitz (voice)

Pamela Adlon

Guest Star

Kunal Dudheker

Emily

Katie Leclerc

The Flash

Brandon Jones

Wil Wheaton

Wil Wheaton

Dr. Alfred Hofstadter

Judd Hirsch

Nolan

Josh Banday

Wyatt Teller

Keith Carradine

Daniel

Bryan Safi

Susan

Katey Sagal

Christopher

Tucker Albrizzi

President Siebert

Joshua Malina

Randall

Jack McBrayer

Jeff

Jareb Dauplaise

Colonel Richard Williams

Dean Norris

Anu

Rati Gupta

Denise

Lauren Lapkus

Mike Rostenkowski

Casey Sander

Michael J. Massimino

Michael J. Massimino

Janine Davis

Regina King

Arthur Jeffries

Bob Newhart

Eric Gablehauser

Mark Harelik

Announcer (voice) / Man / Man V.O. (voice)

Ed Lieberman

Sheldon Cooper

Jim Parsons

Dimitri

Pasha D. Lychnikoff

Aarti Mann

Director

Joel Murray

Director

Mark Cendrowski

Director

Ted Wass

Director

Anthony Rich

Director

James Burrows