Penny

Kaley Cuoco

Leonard Hofstadter

Johnny Galecki

Sheldon Cooper

Jim Parsons

Howard Wolowitz

Simon Helberg

Raj Koothrappali

Kunal Nayyar

Amy Farrah Fowler

Mayim Bialik

Bernadette Rostenkowski

Melissa Rauch

Employee

Efrain Gomez

Doctor Wolcott

Peter MacNicol

Barry Kripke

John Ross Bowie

Stuart Bloom

Kevin Sussman

Georgie

Jerry O'Connell

Mary Cooper

Laurie Metcalf

Janine Davis

Regina King

Nell

Beth Behrs

Arthur Jeffries

Bob Newhart

Oliver

Walter Goggins

President Siebert

Joshua Malina

Bert Kibbler

Brian Posehn

Colonel Williams

Dean Norris

V.M. Koothrappali

Brian George

Mrs. Petrescu

Michelle Arthur

Self

Ira Flatow

Himself

Neil Gaiman

Margaret

Lynn Andrews

Halley Wolowitz (voice)

Pamela Adlon

Bartender

James Maslow

Zack Johnson

Brian Thomas Smith

Himself

Bill Gates

Ruchi

Swati Kapila

Beverly Hofstadter

Christine Baranski

Dr. Samuel

Dana L. Wilson

Kathleen

Rachna Khatau

Pit Boss

Mark Berry

Debbie Wolowitz (voice)

Carol Ann Susi

Mailman

Edward James Gage

Police Officer

Michael Patrick McGill

Ramona

Riki Lindhome

Marcus

Parvesh Cheena

Danielle

Marissa Cuevas

Denise

Lauren Lapkus

Jenna

Ellie Reed

Wil Wheaton

Wil Wheaton

Jess

Caleb Pierce

Stephen Hawking

Stephen Hawking

Wendell

Bob Stephenson

Denise

Brooke Baumer

Grant

Patrick Daniel

Croupier

Evan Charest

Rose Lady

Elka Rodriguez

Cynthia

Megan McGown

Hostess

D'Kia Anderson

Dr. Zhang

George Wyner

Clerk

Nicole Butler

Emily Sweeney

Laura Spencer

Dr. Harris

Susan Chuang

Earl

Seth Coltan

Missy

Courtney Henggeler

Mr. Fowler

Teller

Mrs. Fowler

Kathy Bates

Himself

Mark Hamill

Priya Koothrappali

Aarti Mann

Leslie Winkle

Sara Gilbert

Anu

Rati Gupta

Lucy

Kate Micucci

Mike Rostenkowski

Casey Sander

Michael J. Massimino

Michael J. Massimino

Claire

Alessandra Torresani

Althea

Vernee Watson-Johnson

Eric Gablehauser

Mark Harelik

Announcer (voice) / Man / Lecturer (voice)

Ed Lieberman

Wyatt Teller

Keith Carradine