Sam Winchester

Jared Padalecki

Dean Winchester

Jensen Ackles

Guest Star

Megalyn Echikunwoke

Guest Star

Julie Benz

Meg Masters

Nicki Aycox

Guest Star

Marnette Patterson

Guest Star

Ryan Drescher

John Winchester

Jeffrey Dean Morgan

Guest Star

Brendan Fletcher

Guest Star

Loretta Devine

Castiel / Emmanuel

Misha Collins

Jessica

Adrianne Palicki

Guest Star

Terence Kelly

Mary Winchester

Samantha Smith

Crowley

Mark Sheppard

Bobby Singer

Jim Beaver

Ross Kohn

Rowena MacLeod

Ruth Connell

Jody Mills

Kim Rhodes

Amara / Amara (Adult) / Karin

Emily Swallow

Ruby / Genevieve Padalecki

Genevieve Padalecki

Gabriel / Trickster

Richard Speight Jr.

Charlie Bradbury

Felicia Day

Lisa Braeden

Cindy Sampson

Billie

Lisa Berry

Metatron

Curtis Armstrong

Eli / Benny Lafitte

Ty Olsson

Kelly Kline

Courtney Ford

Donatello Redfield / God

Keith Szarabajka

Adam Milligan / Michael

Jake Abel

Hannah / Caroline Johnson / Young Mother

Erica Carroll

Samuel Campbell / Shapeshifter

Mitch Pileggi

Zachariah

Kurt Fuller

Ellen Harvelle

Samantha Ferris

Meg Masters

Rachel Miner

Eileen Leahy

Shoshannah Stern

Maggie

Katherine Evans

Osric Chau

Mark Pellegrino

Jo Harvelle

Alona Tal

Donna Hanscum

Briana Buckmaster

Balthazar

Sebastian Roché

Claire Novak

Kathryn Newton

Young Sam Winchester

Colin Ford

Rufus Turner

Steven Williams

Liane Balaban

Toni Bevell

Elizabeth Blackmore

Anna Milton

Julie McNiven

Bela Talbot

Lauren Cohan

Ruby

Katie Cassidy

God

Rob Benedict

Edgar

Benito Martinez

Ben Braeden

Nicholas Elia

Gadreel / Ezekiel

Tahmoh Penikett

Mick Davies

Adam Fergus

Pamela Barnes

Traci Dinwiddie

Sister Jo / Anael

Danneel Ackles

Uriel

Robert Wisdom

Michael

Christian Keyes

Asmodeus

Jeffrey Vincent Parise

Belphegor / Jack

Alexander Calvert

Alex Jones

Katherine Ramdeen

Ash

Chad Lindberg

Director

Jeannot Szwarc

Director

Guy Norman Bee

Director

Eduardo Sánchez

Director

Charles Beeson

Director

David Nutter

Director

Richard Speight Jr.

Director

Jensen Ackles

Director

David Jackson

Director

Steve Boyum

Director

P.J. Pesce

Director

James L. Conway

Director

J. Miller Tobin

Director

Mike Rohl

Director

Ken Girotti

Director

Robert Singer

Director

Kim Manners

Director

Peter Ellis

Director

Amyn Kaderali

Director

Thomas J. Wright

Director

Whitney Ransick

Director

John Badham

Director

Tony Wharmby

Director

Allan Kroeker

Director

Robert Duncan McNeill

Director

Paul Shapiro

Director

Nina Corrado