Sam Winchester

Jared Padalecki

Dean Winchester

Jensen Ackles

Guest Star

Mark Pellegrino

Castiel / Emmanuel / Jimmy Novak

Misha Collins

Guest Star

Michael Shanks

Gabriel / Trickster

Richard Speight Jr.

Guest Star

Mark Sheppard

Guest Star

Colton James

Chuck the Prophet

Rob Benedict

Guest Star

Hal Ozsan

Guest Star

Rekha Sharma

Guest Star

Paris Hilton

Guest Star

Lex Medlin

Jessica Moore

Adrianne Palicki

Anna Milton

Julie McNiven

Guest Star

Gattlin Griffith

Bobby Singer

Jim Beaver

Guest Star

Kurt Fuller

Rufus Turner

Steven Williams

Guest Star

Eric Johnson

Guest Star

Keith Blackman Dallas

Guest Star

James Otis

Ellen Harvelle

Samantha Ferris

Guest Star

Carrie Anne Fleming

Guest Star

Matthew Cohen

Guest Star

Roger Aaron Brown

Guest Star

Emily Perkins

Guest Star

Julian Richings

Guest Star

Larry Poindexter

Guest Star

Adam Croasdell

Jo Harvelle

Alona Tal

Guest Star

Kayla Mae Maloney

Guest Star

Amy Gumenick

Guest Star

Matt Frewer

Meg Masters

Rachel Miner

Rowena MacLeod

Ruth Connell

Jack / Belphegor

Alexander Calvert

Mary Winchester

Samantha Smith

Arthur Ketch

David Haydn-Jones

Jody Mills

Kim Rhodes

Amara / Amara (Adult) / Karin

Emily Swallow

Ruby / Genevieve Padalecki

Genevieve Padalecki

Metatron

Curtis Armstrong

Charlie Bradbury

Felicia Day

John Winchester

Jeffrey Dean Morgan

Lisa Braeden

Cindy Sampson

Billie

Lisa Berry

Eli / Benny Lafitte

Ty Olsson

Naomi

Amanda Tapping

Kelly Kline

Courtney Ford

Donatello Redfield / God

Keith Szarabajka

Adam Milligan / Michael

Jake Abel

Hannah / Caroline Johnson / Young Mother

Erica Carroll

Duma / The Shadow / Robin

Erica Cerra

Samuel Campbell / Shapeshifter

Mitch Pileggi

Abaddon

Alaina Huffman

Eileen Leahy

Shoshannah Stern

Maggie

Katherine Evans

Donna Hanscum

Briana Buckmaster

Kevin Tran

Osric Chau

Balthazar

Sebastian Roché

Claire Novak

Kathryn Newton

Young Sam Winchester

Colin Ford

Garth Fitzgerald / Garth Fitzgerald

DJ Qualls

Toni Bevell

Elizabeth Blackmore

Bela Talbot

Lauren Cohan

Ruby

Katie Cassidy

Edgar

Benito Martinez

Ben Braeden

Nicholas Elia

Gadreel / Ezekiel

Tahmoh Penikett

Meg Masters

Nicki Aycox

Mick Davies

Adam Fergus

Pamela Barnes

Traci Dinwiddie

Sister Jo / Anael

Danneel Ackles

Uriel

Robert Wisdom

Michael

Christian Keyes

Asmodeus

Jeffrey Vincent Parise

Alex Jones

Katherine Ramdeen

Kaia Nieves / Dark Kaia

Yadira Guevara-Prip

Ash

Chad Lindberg