Sam Winchester

Jared Padalecki

Dean Winchester

Jensen Ackles

Guest Star

James Patrick Stuart

Guest Star

Nicole Oliver

Castiel / Emmanuel

Misha Collins

Charlie Bradbury

Felicia Day

Guest Star

Russell Sams

Guest Star

Sara Canning

Bobby Singer

Jim Beaver

Death

Julian Richings

Guest Star

Mark Sheppard

Guest Star

Mark Pellegrino

Guest Star

Jason Dohring

Guest Star

Jewel Staite

Guest Star

Faran Tahir

Guest Star

D.J. Qualls

Guest Star

Charisma Carpenter

Guest Star

Kevin R. McNally

Guest Star

Julian Richings

Guest Star

Jamie Luner

Guest Star

Rick Worthy

Meg Masters

Rachel Miner

Jo Harvelle

Alona Tal

Guest Star

Osric Chau

Guest Star

Madison McLaughlin

Guest Star

James Marsters

Guest Star

Nicholas Lea

Mark Pelligrino*

Guest Star

Ian Tracey

Rowena MacLeod

Ruth Connell

Mary Winchester

Samantha Smith

Guest Star

Meghan Ory

Fred Henderson

Paul Herbert

Jody Mills

Kim Rhodes

Tanya Champoux

Amara / Amara (Adult) / Karin

Emily Swallow

Luis Javier

Ruby / Genevieve Padalecki

Genevieve Padalecki

Robert Heimbecker

Gabriel / Trickster

Richard Speight Jr.

Hilary Strang

John Winchester

Jeffrey Dean Morgan

Elizabeth McLaughlin

Lisa Braeden

Cindy Sampson

Sachin Sahel

Billie

Lisa Berry

Metatron

Curtis Armstrong

Eli / Benny Lafitte

Ty Olsson

Kelly Kline

Courtney Ford

Donatello Redfield / God

Keith Szarabajka

Adam Milligan / Michael

Jake Abel

Hannah / Caroline Johnson / Young Mother

Erica Carroll

Samuel Campbell / Shapeshifter

Mitch Pileggi

Zachariah

Kurt Fuller

Ellen Harvelle

Samantha Ferris

Eileen Leahy

Shoshannah Stern

Maggie

Katherine Evans

Donna Hanscum

Briana Buckmaster

Balthazar

Sebastian Roché

Claire Novak

Kathryn Newton

Young Sam Winchester

Colin Ford

Rufus Turner

Steven Williams

Toni Bevell

Elizabeth Blackmore

Anna Milton

Julie McNiven

Bela Talbot

Lauren Cohan

Ruby

Katie Cassidy

God

Rob Benedict

Edgar

Benito Martinez

Ben Braeden

Nicholas Elia

Gadreel / Ezekiel

Tahmoh Penikett

Meg Masters

Nicki Aycox

Mick Davies

Adam Fergus

Pamela Barnes

Traci Dinwiddie

Sister Jo / Anael

Danneel Ackles

Uriel

Robert Wisdom

Michael

Christian Keyes

Asmodeus

Jeffrey Vincent Parise

Belphegor / Jack

Alexander Calvert

Alex Jones

Katherine Ramdeen

Ash

Chad Lindberg

Director

Jeannot Szwarc

Director

Guy Norman Bee

Director

Eduardo Sánchez

Director

Charles Beeson

Director

Richard Speight Jr.

Director

Jensen Ackles

Director

Steve Boyum

Director

P.J. Pesce

Director

James L. Conway

Director

J. Miller Tobin

Director

Mike Rohl

Director

Robert Singer

Director

Kim Manners

Director

Amyn Kaderali

Director

Thomas J. Wright

Director

John MacCarthy

Director

John Badham

Director

Jeannot Szwarc

Director

Nina Corrado