Sam Winchester
Jared Padalecki
Dean Winchester
Jensen Ackles
Guest Star
James Patrick Stuart
Guest Star
Nicole Oliver
Castiel / Emmanuel
Misha Collins
Charlie Bradbury
Felicia Day
Guest Star
Russell Sams
Guest Star
Sara Canning
Bobby Singer
Jim Beaver
Death
Julian Richings
Guest Star
Mark Sheppard
Guest Star
Mark Pellegrino
Guest Star
Jason Dohring
Guest Star
Jewel Staite
Guest Star
Faran Tahir
Guest Star
D.J. Qualls
Guest Star
Charisma Carpenter
Guest Star
Kevin R. McNally
Guest Star
Julian Richings
Guest Star
Jamie Luner
Guest Star
Rick Worthy
Meg Masters
Rachel Miner
Jo Harvelle
Alona Tal
Guest Star
Osric Chau
Guest Star
Madison McLaughlin
Guest Star
James Marsters
Guest Star
Nicholas Lea
Mark Pelligrino*
Guest Star
Ian Tracey
Rowena MacLeod
Ruth Connell
Mary Winchester
Samantha Smith
Guest Star
Meghan Ory
Fred Henderson
Paul Herbert
Jody Mills
Kim Rhodes
Tanya Champoux
Amara / Amara (Adult) / Karin
Emily Swallow
Luis Javier
Ruby / Genevieve Padalecki
Genevieve Padalecki
Robert Heimbecker
Gabriel / Trickster
Richard Speight Jr.
Hilary Strang
John Winchester
Jeffrey Dean Morgan
Elizabeth McLaughlin
Lisa Braeden
Cindy Sampson
Sachin Sahel
Billie
Lisa Berry
Metatron
Curtis Armstrong
Eli / Benny Lafitte
Ty Olsson
Kelly Kline
Courtney Ford
Donatello Redfield / God
Keith Szarabajka
Adam Milligan / Michael
Jake Abel
Hannah / Caroline Johnson / Young Mother
Erica Carroll
Samuel Campbell / Shapeshifter
Mitch Pileggi
Zachariah
Kurt Fuller
Ellen Harvelle
Samantha Ferris
Eileen Leahy
Shoshannah Stern
Maggie
Katherine Evans
Donna Hanscum
Briana Buckmaster
Balthazar
Sebastian Roché
Claire Novak
Kathryn Newton
Young Sam Winchester
Colin Ford
Rufus Turner
Steven Williams
Toni Bevell
Elizabeth Blackmore
Anna Milton
Julie McNiven
Bela Talbot
Lauren Cohan
Ruby
Katie Cassidy
God
Rob Benedict
Edgar
Benito Martinez
Ben Braeden
Nicholas Elia
Gadreel / Ezekiel
Tahmoh Penikett
Meg Masters
Nicki Aycox
Mick Davies
Adam Fergus
Pamela Barnes
Traci Dinwiddie
Sister Jo / Anael
Danneel Ackles
Uriel
Robert Wisdom
Michael
Christian Keyes
Asmodeus
Jeffrey Vincent Parise
Belphegor / Jack
Alexander Calvert
Alex Jones
Katherine Ramdeen
Ash
Chad Lindberg
Director
Jeannot Szwarc
Director
Guy Norman Bee
Director
Eduardo Sánchez
Director
Charles Beeson
Director
Richard Speight Jr.
Director
Jensen Ackles
Director
Steve Boyum
Director
P.J. Pesce
Director
James L. Conway
Director
J. Miller Tobin
Director
Mike Rohl
Director
Robert Singer
Director
Kim Manners
Director
Amyn Kaderali
Director
Thomas J. Wright
Director
John MacCarthy
Director
John Badham
Director
Jeannot Szwarc
Director
Nina Corrado