Sam Winchester

Jared Padalecki

Dean Winchester

Jensen Ackles

Castiel

Misha Collins

Crowley

Mark Sheppard

Bobby Singer

Jim Beaver

Guest Star

Mark Pellegrino

Dee Wallace

Guest Star

Kim Rhodes

Guest Star

Nate Torrence

Amara / Amara (Adult) / Karin

Emily Swallow

Guest Star

Mike "The Miz" Mizanin

Guest Star

Jared Gertner

Guest Star

Curtis Armstrong

Rowena MacLeod

Ruth Connell

Guest Star

Rob Benedict

Guest Star

Aleks Paunovic

John Winchester

Jeffrey Dean Morgan

Claire Novak

Kathryn Newton

Guest Star

Yasmeene Ball

Rufus Turner

Steven Williams

Guest Star

Katherine Ramdeen

Mary Winchester

Samantha Smith

Osric Chau

Ruby / Genevieve Padalecki

Genevieve Padalecki

Ellen Harvelle

Samantha Ferris

Gabriel / Trickster

Richard Speight Jr.

Samuel Campbell / Shapeshifter

Mitch Pileggi

Eli / Benny Lafitte

Ty Olsson

Charlie Bradbury

Felicia Day

Jo Harvelle

Alona Tal

Lisa Braeden

Cindy Sampson

Zachariah

Kurt Fuller

Liane Balaban

Billie

Lisa Berry

Kelly Kline

Courtney Ford

Donatello Redfield / God

Keith Szarabajka

Adam Milligan / Michael

Jake Abel

Hannah / Caroline Johnson / Young Mother

Erica Carroll

Meg Masters

Rachel Miner

Eileen Leahy

Shoshannah Stern

Maggie

Katherine Evans

Donna Hanscum

Briana Buckmaster

Balthazar

Sebastian Roché

Young Sam Winchester

Colin Ford

Toni Bevell

Elizabeth Blackmore

Anna Milton

Julie McNiven

Bela Talbot

Lauren Cohan

Ruby

Katie Cassidy

Edgar

Benito Martinez

Ben Braeden

Nicholas Elia

Gadreel / Ezekiel

Tahmoh Penikett

Meg Masters

Nicki Aycox

Mick Davies

Adam Fergus

Pamela Barnes

Traci Dinwiddie

Sister Jo / Anael

Danneel Ackles

Uriel

Robert Wisdom

Michael

Christian Keyes

Asmodeus

Jeffrey Vincent Parise

Belphegor / Jack

Alexander Calvert

Ash

Chad Lindberg

Director

Jeannot Szwarc

Director

Guy Norman Bee

Director

Eduardo Sánchez

Director

Charles Beeson

Director

Richard Speight Jr.

Director

Jensen Ackles

Director

Steve Boyum

Director

P.J. Pesce

Director

James L. Conway

Director

J. Miller Tobin

Director

Mike Rohl

Director

Robert Singer

Director

Kim Manners

Director

Eduardo Sánchez

Director

Amyn Kaderali

Director

Rashaad Ernesto Green

Director

Thomas J. Wright

Director

John Badham

Director

Nina Corrado