Sam Winchester

Jared Padalecki

Dean Winchester

Jensen Ackles

Castiel / Emmanuel

Misha Collins

Lisa Braeden

Cindy Sampson

Guest Star

Andrew Rothenberg

Guest Star

Katie Walder

Ben Braeden

Nicholas Elia

Guest Star

Julian Richings

Bobby Singer

Jim Beaver

Guest Star

Sam Hennings

Meg Masters

Rachel Miner

Samuel Campbell / Shapeshifter

Mitch Pileggi

Guest Star

Mark A. Sheppard

Guest Star

Julia Maxwell

Guest Star

Sebastian Roche

Mary Winchester

Samantha Smith

Guest Star

Jessica Heafey

Rowena MacLeod

Ruth Connell

Jody Mills

Kim Rhodes

Amara / Amara (Adult) / Karin

Emily Swallow

Ruby / Genevieve Padalecki

Genevieve Padalecki

Gabriel / Trickster

Richard Speight Jr.

Charlie Bradbury

Felicia Day

John Winchester

Jeffrey Dean Morgan

Billie

Lisa Berry

Metatron

Curtis Armstrong

Eli / Benny Lafitte

Ty Olsson

Kelly Kline

Courtney Ford

Donatello Redfield / God

Keith Szarabajka

Adam Milligan / Michael

Jake Abel

Hannah / Caroline Johnson / Young Mother

Erica Carroll

Osric Chau

Mark Pellegrino

Zachariah

Kurt Fuller

Ellen Harvelle

Samantha Ferris

Eileen Leahy

Shoshannah Stern

Jo Harvelle

Alona Tal

Maggie

Katherine Evans

Liane Balaban

Donna Hanscum

Briana Buckmaster

Claire Novak

Kathryn Newton

Young Sam Winchester

Colin Ford

Rufus Turner

Steven Williams

Toni Bevell

Elizabeth Blackmore

Anna Milton

Julie McNiven

Bela Talbot

Lauren Cohan

Ruby

Katie Cassidy

God

Rob Benedict

Edgar

Benito Martinez

Gadreel / Ezekiel

Tahmoh Penikett

Meg Masters

Nicki Aycox

Mick Davies

Adam Fergus

Pamela Barnes

Traci Dinwiddie

Sister Jo / Anael

Danneel Ackles

Uriel

Robert Wisdom

Michael

Christian Keyes

Asmodeus

Jeffrey Vincent Parise

Belphegor / Jack

Alexander Calvert

Alex Jones

Katherine Ramdeen

Ash

Chad Lindberg

Director

Jeannot Szwarc

Director

Eduardo Sánchez

Director

Charles Beeson

Director

Richard Speight Jr.

Director

Jensen Ackles

Director

Steve Boyum

Director

P.J. Pesce

Director

James L. Conway

Director

J. Miller Tobin

Director

Mike Rohl

Director

Guy Bee

Director

Robert Singer

Director

David Barrett

Director

Kim Manners

Director

Amyn Kaderali

Director

Thomas J. Wright

Director

John Badham

Director

Jeannot Szwarc

Director

Rod Hardy

Director

Nina Corrado