Homer Jay Simpson/Barney Gumble/Grampa Simpson/Mayor Joe Quimby/Krusty the Klown/Groundskeeper Willie

Dan Castellaneta

Marjorie Bouvier Simpson/ Patty Bouvier/Selma Bouvier/Grandma Jackie Bouvier

Julie Kavner

Lisa Simpson (voice)

Yeardley Smith

Bart Simpson / Nelson Muntz / Ralph Wiggum (voice)

Nancy Cartwright

Charles Montgomery Burns/Waylon Smithers/Principal Seymour Skinner/Ned Flanders/Otto Mann/Scratchy/Kent Brockman/Dr. Julius Hibbert/Reverend Timothy Lovejoy

Harry Shearer

Moe Szyslak/Apu Nahasapeemapetilon/Chief Clancy Wiggum/Dr. Nick Riviera

Hank Azaria

Bleeding Gums Murphy

Ron Taylor

Hugh St. John Alastair Parkfield

Mandy Patinkin

Guest Voice

Milton Berle

Ballet Teacher

Susan Sarandon

Monkeys / Princess (voice) / Executive Vice-President (voice)

Frank Welker

Himself

Dennis Franz

Agnes Skinner (voice) / Dolph (voice) / (voice)

Tress MacNeille

Milhouse Van Houten (voice) / Milhouse (voice) / Milhouse Van Houten

Pamela Hayden

Jacques (voice) / Hank Scorpio (voice) / Tab Spangler

Albert Brooks

Llewellyn Sinclair (voice) / Artie Ziff (voice) / Enrico Irritazio (voice)

Jon Lovitz

Edna Krabappel (voice) / Crowd (voice) / Edna Krabappel

Marcia Wallace

Jessica Lovejoy

Meryl Streep

Number One

Patrick Stewart

Allison Taylor

Winona Ryder

Sideshow Bob (voice)

Kelsey Grammer

Himself

Dick Cavett

Maggie Simpson

James Earl Jones

Dr. Zweig

Anne Bancroft

Himself

Mel Brooks

Fat Tony (voice) / Gordus Antonius (voice)

Joe Mantegna

Guest Voice

Kareem Abdul-Jabbar

Lunchlady Doris (voice) / Ice cream lady (voice) / Della (voice)

Doris Grau

Maude Flanders (voice) / Luann Van Houten (voice) / Helen Lovejoy (voice)

Maggie Roswell

Dr. Demento

Barry Hansen

Himself

Steve Allen

Sam Malone

Ted Danson

Laura Powers

Sara Gilbert

Troy McClure (voice) / Lionel Hutz (voice) / Lionel Hutz

Phil Hartman

Carla Tortelli

Rhea Perlman

Himself

Johnny Unitas

Orson Welles (voice) / (voice) / Chef Naziwa

Maurice LaMarche

Martin Prince (voice) / Martin Prince / Sherri

Russi Taylor

Himsef

Tito Puente

Norm Peterson

George Wendt

Himself

Larry King

Additional Voices (voice) / (voice) / Prisoners

Karl Wiedergott*

Woody Boyd

Woody Harrelson

Norbert Gastell

Mindy Simmons

Michelle Pfeiffer

Cliff Clavin

John Ratzenberger

Fred Flintstone

Henry Corden

(voice) / Additional Voices (voice) / Laughing Crowd (voice)

Chris Edgerly

Elisabeth Volkmann

Sandra Schwittau

Krusty the Clown Show Announcer

Michael Carrington

Sabine Bohlmann

Dr. Hibbert (voice) / Narrator (voice) / Jay G (voice)

Kevin Michael Richardson

Carl Carlson (voice) / Lou (voice) / Carl Carlson

Alex Désert

Martin Prince (voice) / Sherri / Terri (voice)

Grey DeLisle

Bernice Hibbert (voice) / (voice) / Cannabis Influencer (voice)

Dawnn Lewis

Mona Simpson (voice)

Glenn Close

Kumiko Albertson (voice) / Truth-Anne (voice) / Band Student (voice)

Jenny Yokobori

Hyman Krustofsky (voice)

Jackie Mason

Helen Lovejoy (voice) / Maude Flanders (voice) / Miss Hoover (voice)

Marcia Mitzman Gaven

Julio Franco (voice) / Julio (voice) / Audience

Tony Rodriguez

Constance Harm (voice) / Judge Harm (voice)

Jane Kaczmarek

Lewis Clark (voice) / Janine Powell (voice) / Kindergartener (voice)

Kimberly Brooks

Susan / Collette the Waitress (voice) / Weasel #2

Jo Ann Harris

Manjula Nahasapeemapetilon (voice)

Jan Hooks

Rayshelle Peyton (voice)

Kerry Washington

Backstage Mom (voice) / Mrs. Butterworth (voice) / Old Lady (voice)

Valerie Harper

Howard K. Duff VIII (voice) / Don Bookner (voice) / Howard Duff (voice)

Stacy Keach

Murphy (voice) / Dana Gould (voice) / I.N.S. Agent (voice)

Dana Gould

Dr. Lionel Budgie (voice) / Nigel (voice) / Clayton (voice)

Michael York

Bumblebee Man (voice) / Lisa's Student (voice) / Gambling Old Man (voice)

Eric Lopez

Stephen Hawking (voice)

Stephen Hawking

Sarah Wiggum (voice)

Megan Mullally

Akira Kurosawa (voice) / Wink - The Game Show Host (voice) / Waiter (voice)

George Takei

J. Jonah Jameson (voice) / Victor Kleskow (voice) / Tabloid Editor (voice)

J.K. Simmons

Director

Mark Kirkland

Director

Jennifer Moeller

Director

Neil Affleck

Director

Chuck Sheetz

Director

David Silverman

Director

Lauren MacMullan

Director

Dominic Polcino

Director

Swinton O. Scott III

Director

Rich Moore

Director

Raymond S. Persi

Director

Debbie Bruce Mahan

Director

Pete Michels

Director

Mike B. Anderson

Director

Matthew Faughnan

Director

Michael Polcino