Homer Jay Simpson/Barney Gumble/Grampa Simpson/Mayor Joe Quimby/Krusty the Klown/Groundskeeper Willie

Dan Castellaneta

Marjorie Bouvier Simpson/ Patty Bouvier/Selma Bouvier/Grandma Jackie Bouvier

Julie Kavner

Lisa Simpson (voice)

Yeardley Smith

Bart Simpson / Nelson Muntz / Ralph Wiggum (voice)

Nancy Cartwright

Moe Szyslak/Apu Nahasapeemapetilon/Chief Clancy Wiggum/Dr. Nick Riviera

Hank Azaria

Charles Montgomery Burns/Waylon Smithers/Principal Seymour Skinner/Ned Flanders/Otto Mann/Scratchy/Kent Brockman/Dr. Julius Hibbert/Reverend Timothy Lovejoy

Harry Shearer

Himself

Paul McCartney

Erin

Christina Ricci

Himself

Peter Frampton

Agnes Skinner (voice) / Dolph (voice) / (voice)

Tress MacNeille

Hollis Hurlbut

Donald Sutherland

Fat Tony (voice) / Gordus Antonius (voice)

Joe Mantegna

Mona Simpson (voice)

Glenn Close

Chester J. Lampwick

Kirk Douglas

Don Brodka

Lawrence Tierney

Himself

Tom Kite

Himself

Paul Anka

Sideshow Bob (voice)

Kelsey Grammer

himself

Tito Puente

Himself

Bob Newhart

Woman on Phone

Joan Kenley

Bill Gannon

Harry Morgan

Herself

Kim Gordon

Himself

Mickey Rooney

Herself

Suzanne Somers

Milhouse Van Houten (voice) / Milhouse (voice) / Milhouse Van Houten

Pamela Hayden

himself

Buzz Aldrin

Herself

Linda McCartney

Guest Voice

Daryl Gates

MacArthur Parker

Jeff Goldblum

Colonel Leslie Hapablap

R. Lee Ermey

Troy McClure (voice) / Lionel Hutz (voice) / Lionel Hutz

Phil Hartman

Roger Meyers Jr.

Alex Rocco

Himself

B-Real

Edna Krabappel (voice) / Edna Krabappel / Ms. Melon (voice)

Marcia Wallace

Lead Vocalist

George Balmaseda

Hong Kong Doctor

Jim Lau

Lunchlady Doris (voice) / Ice cream lady (voice) / Lunchlady (voice)

Doris Grau

Himself

DJ Muggs

Maude Flanders (voice) / Helen Lovejoy (voice) / Luann Van Houten (voice)

Maggie Roswell

Martin Prince (voice) / Martin Prince / Sherri

Russi Taylor

Himself

Sen Dog

Lord Nibbler (voice) / Baboons (voice) / Santa's Little Helper

Frank Welker

The Amendment

Jack Sheldon

Santa in Bart's fantasy

Josh Weinstein

Maggie Simpson

Liz Georges

(voice) / Additional Voices (voice) / Laughing Crowd (voice)

Chris Edgerly

Himself

Billy Corgan

Additional Voices (voice) / (voice) / New England Church Members (voice)

Karl Wiedergott*

Herself

D'Arcy

Norbert Gastell

Himself

Jimmy Chamberlin

Himself

Thurston Moore

Dr. Hibbert (voice) / Narrator (voice) / Security Guard (voice)

Kevin Michael Richardson

Sandra Schwittau

Carl Carlson (voice) / Lou (voice) / Carl Carlson

Alex Désert

Himself

Lee Ranaldo

Himself

Steve Shelley

Himself

James Iha

Martin Prince (voice) / Sherri / Terri (voice)

Grey DeLisle

Bernice Hibbert (voice) / (voice) / Flight Attendant (voice)

Dawnn Lewis

Orson Welles (voice) / (voice) / Jock #2 (voice)

Maurice LaMarche

Llewellyn Sinclair (voice) / Enrico Irritazio (voice) / Artie Ziff (voice)

Jon Lovitz

Kumiko Albertson (voice) / Truth-Anne (voice) / "It Will Get Better" Girl (voice)

Jenny Yokobori

Hyman Krustofsky (voice)

Jackie Mason

Maude Flanders (voice) / Helen Lovejoy (voice) / Miss Hoover (voice)

Marcia Mitzman Gaven

Jacques (voice) / Hank Scorpio (voice) / Brad Goodman (voice)

Albert Brooks

Constance Harm (voice) / Judge Harm (voice)

Jane Kaczmarek

Janine Powell (voice) / Lewis Clark (voice) / Lewis (voice)

Kimberly Brooks

Julio (voice) / Julio Franco (voice) / Audience

Tony Rodriguez

Weasel (voice) / Richard / Lewis (voice)

Jo Ann Harris

Manjula Nahasapeemapetilon (voice)

Jan Hooks

Rayshelle Peyton (voice)

Kerry Washington

Backstage Mom (voice) / Ms. Myles (voice) / Jennifer Clarkeson (voice)

Valerie Harper

Howard K. Duff VIII (voice) / Don Bookner (voice) / Howard K. Duff VIII

Stacy Keach

Murphy (voice) / Dana Gould (voice) / I.N.S. Agent (voice)

Dana Gould

Dr. Lionel Budgie (voice) / Clayton (voice) / Nigel (voice)

Michael York

Bumblebee Man (voice) / Lisa's Student (voice) / Gambling Old Man (voice)

Eric Lopez

Stephen Hawking (voice)

Stephen Hawking

Sarah Wiggum (voice)

Megan Mullally

Waiter (voice) / Akira Kurosawa (voice) / Sushi Chef (voice)

George Takei

JJ Gruff (voice) / J. Jonah Jameson (voice) / Dr. Jessup (voice)

J.K. Simmons

Director

Mark Kirkland

Director

Neil Affleck

Director

Chuck Sheetz

Director

David Silverman

Director

Lauren MacMullan

Director

Dominic Polcino

Director

Swinton O. Scott III

Director

Rich Moore

Director

Raymond S. Persi

Director

Debbie Bruce Mahan

Director

Pete Michels

Director

Jennifer Moeller

Director

Mike B. Anderson

Director

Matthew Faughnan

Director

Michael Polcino